What does MRE in depression stand for?

In this brief guide, we will be discussing what does MRE in depression stand for. We will also discuss other disorders related to depression, its signs and symptoms and we will be answering frequently asked questions about the subject.

It is normal for us all to experience mood swings and feel like we are “depressed” within a day brought about by different factors, situations and our mental state. However, if this distresses a person due to its excess and if it lasts for days, then this might become a problem. Not only for the person themselves but for the people around them as well.  

 What does MRE stand for in depression?

MRE stands for Most Recent Episode and this is used in diagnosing an individual with Bipolar Disorder.

Below are some examples from the ICD-10 Codes.

·         Bipolar disorder, in full remission, MRE hypomanic

·         Bipolar disorder, in partial remission, MRE manic

·         Bipolar disorder, in full remission, MRE manic

·         Bipolar disorder, in partial remission, MRE depressed

·         Bipolar disorder, in full remission, MRE depressed

·         Bipolar disorder, in partial remission, MRE episode mixed

·         Bipolar disorder, in full remission, MRE mixed

Diagnosing someone with bipolar, a mental health professional will specify and indicate in the diagnosis and the medical record of the client if there is a recent episode that came along with it.  

What is depression?

Depression is a psychological disorder that negatively affects the way we think, feel and behave and which causes danger, distress, dysfunctionality at home and/or in school or work and may deviate one from most people.

There are many signs and symptoms that one may have before being diagnosed with it. At least 5 of the following symptoms should be present before being diagnosed with depression during the 2-week period and at least either or both symptoms, depressed mood or loss of interest or pleasure is present:

– most days in a depressed mood, nearly everyday as observed by one’s self and/or others. (note: children may show agitation)

– anhedonia or loss of interest in pleasurable activities

– drastic weight loss or weight gain

– unfocused or diminished thinking


– feelings of unworthiness

– psychomotor agitation

– having recurring thoughts of suicide or death

– lack of sleep or excessive sleep

Structure of Mood Disorders/Depression

Mood Disorders can be unipolar or bipolar. A person may experience only one or both depending on many factors such as the biological make up, psychological state and social interaction or conditions of a person.

The following are some specifiers for mood disorders/depression:

·        mixed features – ambivalence or feeling depressed or anxious to some degree or depressed with symptoms of mania at the same time

·        dysphoric – characterized by feelings of anxiety and depression

·        psychotic features – With hallucinations and/or delusions. This can be somatic (relating to body), auditory hallucinations may also manifest (these are considered mood congruent) and other types might have delusions of grandeur (mood-incongruent).

·        anxious distress – accompanied by anxiety

·        melancholic features – characterized by anhedonia, weight loss, early morning awakenings, loss of libido (sex drive) and may signify a severe or higher level of depressive episode

·        atypical feature – It is characterized by oversleeping and overeating. May not necessarily show lethargy or loss of interest. Common among people others think will not commit suicide.

·        peripartum onset – occurs surrounding the time of pregnancy and birth. May be associated with high levels of corticotropin-releasing hormone, part of the HPA axis.

·        catatonic specifier – Catalepsy or absence of movement. This is a rare among people experiencing depression/mood disorders.

·        seasonal pattern – Symptoms are associated with changes in weather. A person may be depressive during the winter and seem normal during summer.

What are disorders associated with depression?

Disorders associated with depression are the following:

·        Major Depressive Disorder (MDD) or commonly known as Depression itself

·        Persistent Depressive Disorder (PDD or Dysthymia or Double Depression)

·        Premenstrual Dysphoric Disorder

·        Disruptive Mood Dysregulation Disorder

·        Cyclothymic Disorder

·        Bipolar I Disorder

·        Bipolar II Disorder

These are the disorders under the same umbrella in the Diagnostic and Statistical Manual of Mental Disorder edition 5.  Before we move forward with knowing more about MRE Depression, we will explore the characteristics of bipolar.

What is Bipolar?

Bipolar Disorder is the new term for the old diagnosis manic-depressive illness or manic depression). It is a psychological disorder under the Mood Disorders characterized by mania and depression.

This disorder can disrupt patterns of sleep, thinking, feeling, behaving in an immensely fluctuating way. A person may experience heightened emotions and flight of ideas and thoughts when in a manic episode within a period of time and shift to a depressive episode that will also last for a certain amount of time.


A manic episode is characterized by significantly increased goal-oriented activities, heightened energy, sense of self, expansive or irritable mood. It is also common to experience euphoria for people experiencing mania.

Signs and symptoms of mania are as follows:

·        abnormally high optimism

·        grandiose sense of self, beliefs, abilities or powers

·        significantly has less need for rest and sleep but maintaining heightened energy

·        talks very fast

·        flight of ideas

·        feeling jumpy

·        racing thoughts from one to another

·        distractibility

·        inability to focus

·        reckless behaviors without discerning on its consequences

·        hallucinations and delusions in severe cases

Hypomania symptoms

Symptoms of hypomania are similar to mania’s. However, the individual does not lose touch with reality. This is a subthreshold of a manic episode. From an outsider, this may be viewed merely as an unusually bright and good mood. However, hypomania can result in impairment in decision making that may affect relationships, reputation and career, and this may lead to a manic episode. This must be present for at least 4 days.

Major Depressive Episode

Common symptoms of a major depressive episode (MDE) must be present during the same two-week period. At least one or either is present: (a) depressed mood or (b) loss of interest or pleasure and at least 5 of the symptoms below is present:

·         Feeling hopelessness and helplessness

·         significantly decreased interest and desire for pleasurable activities or in almost all activities

·         significant weight loss

·         hypersomnia or insomnia

·         physical and mental sluggishness

·         inability to focus

·         feelings of exhaustion

·         depressed mood

·         recurrent thoughts of death and suicidal ideation  

Bipolar is more than just fleeting moods, feelings, thoughts and emotions. This may interfere with our functioning at home, school and/or work, our relationships and disrupt our ability to do our daily activities.

Bipolar I Disorder

Commonly known as manic-depressive disorder or manic depression as known then. Characterized by having at least one manic episode during their lifetime. A person diagnosed with Bipolar I does not necessarily experience a major depressive episode, but possible.

Bipolar II Disorder

A person diagnosed with Bipolar II does not necessarily need to experience manie. But must experience at least one major depressive episode or hypomania.


Cyclothymia is a milder form of bipolar disorder. Manic episode and major depressive disorder must not be present and fluctuations of mood must be present for at least two years.

FAQs: What does MRE in depression stand for?

 What does MRE stand for in depression?

MRE stands for Most Recent Episode and this is used in diagnosing an individual with Bipolar Disorder.

What is rapid cycling?

Rapid cycling is experiencing more than four or four episodes of manic episodes and depression within 12 months. Intermittently manic and depressive. When not adequately treated, a person may dangerously feel out of control. This is commonly experienced by people with bipolar or symptoms of bipolar.

What are the 4 types of bipolar disorder?

The 4 types of bipolar disorder according to the American Psychiatric Association:
·        Bipolar I Disorder
·        Bipolar II Disorder
·        Cyclothymic Disorder
·        Bipolar due to another medical or substance abuse disorder

What are 5 signs of bipolar?

There are many signs of bipolar, and the two major that summarizes it are mania and major depressive episodes. Below are the following signs of bipolar:
·        excessive energy
·        increased agitation, energy and activity
·        risky sexual behaviors
·        decreased need for sleep
·        grandiose sense of self and self-confidence
·        unusually talkative
·        distractibility
·        unable to focus
·        risky and impulsive gambling
·        flying thoughts
·        emotional highs and lows
·        feelings of hopelessness
·        feelings of worthlessness
·        lost interest in pleasurable activities

What does a bipolar episode look like?

Bipolar experiences two highs and lows of mood during its course. During manic episodes, an individual will experience heightened emotions, energy, feelings and may experience euphoria. If a person experiences a manic episode, there is much less need for sleep, tends to become hyperactive, exhibit risky sexual behaviors and can become immensely creative.
On the other hand, a major depressive episode, a person may experience the complete opposite of what was mentioned above.

What does dysphoric hypomania feel like?

Dysphoric Hypomania is experiencing both feelings of mania and depression at the same time. This is commonly known as mixed episode or mixed state. A person’s thoughts and thinking may be raising, there is trouble sleeping, negative mood and sadness, feeling jumpy, fast speech and crankiness are one of the many signs and symptoms.

What is Type 3 bipolar?

A type 3 bipolar is commonly known to be “Cyclothymic Disorder”. It is a mild form of bipolar. What makes it different with Bipolar I and Bipolar II is the spectrum of the mood it reaches. In both bipolar disorders, a person may experience mania and/or major depressive episodes, while a person with cyclothymia does not.
The fluctuation of mood swings of a person with cyclothymia occurs within two years.  

Can bipolar go away?

No, it cannot. Bipolar does not necessarily go away. In diagnosing a psychological disorder, a person’s condition may be classified as good (meaning the mental condition will go away at some point in their lives or go away by itself like depersonalization) or guarded (it is less likely the mental condition will go away like schizophrenia). This may require a lifetime treatment and social support.   
However, symptoms of bipolar can be alleviated with treatments and psychotherapy.  

Can bipolar people tell they are bipolar?

Yes, they can. But not all people who have bipolar disorder know they have a bipolar. During manic episodes, a person may experience a grandiose sense of self, excessive self-confidence and euphoria., These states are so heightened that they do not realize they are having a manic episode.

How can I tell if I am bipolar?

You can tell if you have bipolar if you experience symptoms of mania and depression. Although these experiences may be disturbing for you, it is not appropriate to make a self-diagnosis. Go to your mental health care provider and have yourself checked. Only a certified mental health professional such as a psychiatrist and a psychologist have the authority to diagnose someone with bipolar.

What should you not say to someone with bipolar?

These are few things you should not say to someone with bipolar
“You’re Just Overreacting Again”
“Anything That Doesn’t Kill You Makes You Stronger”
“Everybody Has Mood Swings Sometimes”
“Everyone’s a Little Bipolar Sometimes”
“You Are Psycho”
“You’re Acting Like a Maniac”
“I Wish I Was Manic so I Could Get Things Done”
“But you seem so normal”
It must be your time of the month

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In this brief guide, we discussed what does MRE in depression stand for. We also  discussed other disorders related to depression, its signs and symptoms and answered frequently asked questions about the subject.




Abnormal Psychology: An Integrative Approach: Book by David H. Barlow and V. Mark Durand

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