Is Noopept good for depression? (+Understanding how it works)

This article will explain if Noopept, a type of Nootropics, is good in helping people with depression, and why that happens. The article will explain what Nootropics do, and what are the causes of depression to clarify why Noopept may be good to treat it.

Is Noopept good for depression?

Yes, it has been shown that Noopept not only helps with depression but also with anxiety. Because it improves the person’s cognitive skills, it can help in those symptoms of depression. And since it may make people more active, it can also help them look at depression from a new perspective.

But let’s learn more about Noopept, and the main causes of depression, so we can better understand how Noopept works.

What is Noopept?

Noopept, a form of nootropic, is a peptide-derived one. It is connected to the racetam family. But it is more potent than Piracetam, for example. Noopept works in receptors of dopamine, and serotonin. It also increases Beta and Alpha waves, which increases the person’s level of relaxation. Improving your sense of joy.

Noopept hardly has any side effects, when someone experiences them, it will most likely be related to taking too much of it. The person may experience headaches, jitters, anxiety, brain fog, insomnia, confusion, and overstimulation.

There haven’t been enough studies to discuss its long-term side effects of it. And some people have referred to experiencing side effects when they don’t take Noopept without a choline supplement. Those are necessary to make the brain’s acetylcholine system function. Which will make the Noopept more effective.

Since the dosage of it can lead to side effects, you should be careful about it. The common dose is between 20-and 30mg. But if you are taking the sublingual form, keep in mind its effect is 10 times the dosage, so you should only take between 3-10mg. 

To take the sublingual dose, you need to measure the appropriate dose of powder in a spoon. Put it under your tongue and leave it there for up to three minutes. It will be absorbed, and then you can wash your mouth.

It is suggested that if you experience side effects while taking it, you should try again with a lower dosage. And if you are deciding to take Noopept, you should know that it, and most forms of Nootropics, are not to be mixed with some types of antidepressants such as SSRIs, MAOIs, and Tricyclics.

What are the causes of depression?

Depression is a mental illness that seems to be caused by multiple factors. It seems to be related to genetic factors, meaning that when a person has a family history of depression, it can make it easier for them to be depressed. 

Aside from that, depression may be related to experiencing a traumatic experience, such as the loss of a loved one, or the end of a relationship. And besides that, it has been discovered that depression may be related to a chemical imbalance in the person’s brain. 

It seems that a problem with the person’s neurotransmitters, such as serotonin, dopamine, GABA, Glutamate, Norepinephrine, and Acetylcholine can be related to depression. And that taking something that will boost the neurotransmitter, or their reuptake effect, can improve the symptoms of depression.

What are the most common symptoms of depression?

Depression affects the person in a lot of aspects. It can make them feel intense sadness, emptiness, and as if they have lost their purpose in life. Aside from that, they can lose interest in things, even what they used to love, and it may be hard for them to keep focused on something.

It also leads the person to have a lower sense of self-worth, and low self-esteem. Along with making the person isolated, more irritable, guilty, and ashamed. It can change the person’s eating and sleeping patterns, and cause the person to experience crying spells. 

The person can feel less energetic and experience fatigue. Finally, depression can lead the person to consider self-harm and have thoughts of death, or even suicidal thoughts.

So what are the benefits of Noopept for people with depression? 

As with many Nootropics, Noopept has been used for people that are depressed, and that are looking for medications that don’t have such intense side effects as the ones psychiatrists may prescribe. 

Some people may prefer it since it’s also something natural. And research has shown that 54% of women with depression were using alternative medicine to treat it.

It seems that Noopept has many benefits for people with depression. It can help the person in many aspects that affect people with depression. First, it can improve the person’s memory. 

It makes the person’s short and long term memory better by enhancing something called a brain-derived neurotrophic factor. This makes it easier for the person to retain information, which is great for people with depression since they have trouble focusing.

It can also improve your verbal fluency, making it easier for you to think clearly, and articulate your thoughts better, which can help when you are depressed and experience brain fog. 

Noopept seems to have a stimulating aspect for some people, and although some may be highly sensitive to it, and develop anxiety, most people will feel more prepared and motivated to do things. 

But one should keep in mind that changing a path in depression treatment takes some time. Don’t do it from one day to the next. You may want to discuss it with your psychiatrist about it, and understand their view on the matter.

They may support it or not, and at the end of the day, the decision is up to you. So if you are certain you want to stop your conventional antidepressant, ask them how it’s the best way to do so, and they will teach you so you don’t experience intense symptoms of withdrawal. And when you stop, you can start with Noopept.

Frequently Asked Questions (FAQ): Is Noopept good for depression? 

Are nootropics safe for long-term use?

It is not yet known if nootropics are safe for long-term use. There hasn’t been enough time, or any conclusive studies that show what can be the long term effects nootropics will have on the person’s brain.

What are the most common side effects of nootropics?

The most common side effects when people take a higher dose of nootropics are blurry vision, insomnia, high blood pressure, fast heartbeat, circulation problems, and it may even lead to addiction.

What can happen if I take Noopept before sleep?

Taking Noopept before sleeping is called Noopept sleep, and it is usually not recommended for people to take it before bedtime. That is because it can cause the person to experience sleep disturbance, which can in turn make the person more irritable, and also increase their blood pressure. 

What is the biggest problem in taking a nootropic?

The biggest problem when considering taking nootropics is that you are dealing with a lot of uncertainty. Unlike antidepressants that have been on the market for years, and have been studied in-depth, there are still many studies going on with nootropics, and some questions that people are not even trying to answer still. 

So if you decide to take them, you should do so taking this under consideration. You will be exposing yourself, your body, to something no one is exactly sure how it will affect it on the long hall. 

Does depression have a cure? 

No, depression doesn’t have a cure. Rather than that, mental health professionals prefer to say that a person will go into remission when their depression starts to improve. It is like that because it is impossible to say to a person that, once they feel better, they will never have another depressive episode again.

That is because there is a genetic factor to depression, which is not possible to change with any sort of treatment. But even though this can sound worrying for people with depression, they can rest assured that when they go into remission their symptoms will improve, and they will be able to experience joy, and regain interest in things once again.

And once they feel better, they need to keep caring for their mental health, as a way to try and prevent future relapse.

Does medication work differently in each person?

Yes, medication will usually work differently from one person to the next. That is why it is important to be followed by a professional. Two people may be taking the same medication, with the same dosage, for the same condition, and react completely differently from one another.

While one may experience intense side effects, and not feel any improvement with the medication, to a point it may need to be changed. The other person may experience a significant improvement. Medications, especially mental health medications are a process.

Even though your doctor will prescribe one for your condition, they will only know the side effects and how you will react, after you take it.

What are the types of antidepressants?

Antidepressants are the type of medication people take when they are going through a depressive episode, and sometimes are associated with other medications to treat other conditions.

The most commonly prescribed is Selective serotonin reuptake inhibitors (SSRIs). Doctors tend to prescribe it more because they usually have fewer side effects, two examples of it are Fluoxetine and Citalopram.

Another form of antidepressant is the Serotonin-noradrenaline reuptake inhibitors (SNRIs). It is similar to SSRIs but was created to be more effective than SSRIs. The most common medication for SNRIs is venlafaxine.

Noradrenaline and specific serotonergic antidepressants (NASSAs) are recommended for people that can’t take SSRIs. They have some side effects that need to be taken into consideration such as dizziness, but it affects the person’s libido less than SSRIs. An example of it is mirtazapine.

One of the older forms of antidepressants such as tricyclic antidepressants (TCAs), they can be recommended to people with major depression that are resistant to other medications. An example of it is amitriptyline. 

Serotonin antagonists and reuptake inhibitors (SARIs) are a form of antidepressants that is also prescribed when other forms haven’t worked. An example of it is trazodone. 

Monoamine oxidase inhibitors (MAOIs) are also an older type of antidepressant. It has a lot of serious side effects. The most known example of it is tranylcypromine.


This article centered on explaining why Noopept may help people going through depression. It showed what are Nootropics, and what are the main causes of depression, to explain how Noopept may help improve symptoms of depression.

If you have any questions or comments about this article, feel free to write it in the section below.


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