Immediate resignation letter due to illness (Samples)

In this brief blog post, we will provide examples of immediate resignation letter due to illness.

Immediate resignation letter due to illness

An immediate resignation letter due to illness is a very unfortunate scenario, this can happen when you have received news from a relative that needs your immediate attention and full-time availability or it can also happen that you have received a diagnosis that requires your immediate attention to yourself in order to get better or to keep a medical condition under control, avoiding the worsening of symptoms.  

If you are experiencing any of the scenarios we have mentioned, then here are some examples of how to write your immediate resignation letter due to illness.

Sample 1 immediate resignation letter due to illness

“Dear Sir/Madam,

Resignation from the position of XXXX

Further to our recent conversations, I am very sorry to confirm that I have no other alternative but to hand my notice in with immediate effect due to illness.

I am unable to continue working and have been signed off sick by my doctor who feels that I will be unable to return to work in the future. As this is the case I feel that I need to take this opportunity to concentrate on my illness and trying to look at my recovery and wellbeing.

I am sorry that in this situation that I am unable to give you any notice to leave COMPANY NAME but I am very grateful for all the opportunities you have given me over X years/months. I feel that COMPANY NAME has a very good future and I am sorry not to be able to be part of that.

You may contact me via phone or email should there be any questions regarding my work or anything that you need to know but I hope that I have left everything in a good order for someone to pick up.

Thank you again, please could you forward me any outstanding monies and my P45 to my home address.

Wishing you all well for the future.

Best Wishes.

Yours sincerely


Sample 2 immediate resignation letter due to illness

“(000) 878-0000

June 17, 2019

Mr. Phillip Barlow

Human Resources Manager 

Hamilton Inc.

3637 Northbrook Avenue N

New York, NY 98989

Brooklyn Park, MN 73982

Dear Mr. Barlow:

It is with much regret that I inform you of my decision to resign immediately from my position as Account Manager for Hamilton Inc. As you know, I took a lot of time off from work due to numerous hospital visits. I believe that it is time to take a break as stress is a contributing factor to my illness.

Three weeks ago, I was diagnosed with Multiple Sclerosis (MS), a diagnosis that has brought my life to a screeching halt. I enjoyed working at Hamilton Inc, and it feels quite odd to me that I will not be associated with the company in the future. While I am not ready for retirement as yet, I have no choice but to resign. During my hiatus, I intend to take this experimental drug for MS that my doctor has advised. I hope that I will be able to get back to work after a couple of years.

I understand that I need to provide notice of my intent to leave. 

Unfortunately, I am not well enough to work during the notice period which is why I have asked for an immediate release. Had the circumstances been slightly different, I would not have taken this hard decision.

I would appreciate it if you could arrange for my leaving documents as soon as possible as I am applying for my social security disability benefits this week. However, I will be available on an on-and-off basis if you would like me to train the person who will replace me.


Paul Rock

(000) 878-0000”

Sample 3 immediate resignation letter due to illness

In this scenario, there is an example of an immediate resignation letter due to illness but referring to a spouse being ill. 

“Anthony Stark

58 West Street # 212

Bear, DE 25152

(521) 965-2010

Anathoney @ email . com

August 31, 2016

Mr. Thomas Hanks

Marketing Manager

Global Elite Group

41 Harrison Avenue

Bear, DE 23870

Dear Mr. Hanks:

With much regret and extreme sadness, I am writing this letter to inform you of my decision to resign from my position as Marketing Officer for Global Elite Groups, with immediate effect. By the end of today, I will hand over all my work to you, along with all the key cards that I was issued.

I understand that according to the contract, I have to provide a 2-week notice of my intention to resign. I am afraid that this is not possible right now. My wife was diagnosed with terminal cancer (Stage 4 – Ovarian) and I want to be with her during this time of extreme despair. As is proper, I am assigning myself as her caregiver, as I want to give her palliative care with love and sincerity.

If possible, please issue me a reference letter at your earliest convenience – I would also appreciate it if you would expedite my salary as it is the end of the month. I appreciate your concern and understanding at this difficult time in my life.



Anthony Stark”

Sample 4 immediate resignation letter due to illness

“Mr Joe Bloggs

1 High Street


X1 2YZ

Mrs J Smith

Senior Supervisor

ABC Solutions

147 The Street


Z9 8YX


Dear Mrs Smith

Please accept this letter as notification that I wish to resign from my position as Administrative Assistant within ABC Solutions, with effect from the date above.

It is with a heavy heart that I leave the position which I have assumed for the past eight years, but due to on-going ill health, I find it is no longer possible to continue my duties with the company.

I believe I am required to give you four weeks’ notice of my intentions; therefore my date on which I depart will be (insert date). As I am currently on sick leave, it is my understanding that I am not eligible to take my accrued holiday entitlement. Please advise me if this will be paid to me and, if so, when.

May I take this opportunity to thank you most graciously for the help, support, and opportunities I have had in the fantastic years I have been with the company. It has been a remarkable experience and I feel I have gained a lot of knowledge that I can take with me into my future pursuits.

Should you require any additional information from me, do not hesitate to contact me.

Yours sincerely

Joe Bloggs”

Other sample resignation or leave letters

Below are some of the other resignation or leave letters we curated.

If you are looking for a job, you should also ideally start your job research on job websites such as Indeed.

Resignation letter sample f&b
Resignation letter sample in Kannada
Resignation letter sample Kuwait
Leave of absence letter for vacation
Sample resignation letter due to family matters

If you are suffering from depression, anxiety, loneliness or any similar mental health issue then seeking help for it may be a good option.

Mental health issues such as depression, loneliness and anxiety can affect anyone of us.

If you are under 18 then CAMHS, an NHS run program may just be the answer for your mental health struggles.

You should look to see if you meet the CAMHS referral criteria and then fill in the CAMHS referral form.