How long does it take for the increased dosage of Fluoxetine to work?

This article will explain how long it takes for your higher dosage of fluoxetine to work. For that, the article will explain what Fluoxetine is, how it works in the person’s system, what it is used for, and its main side effects.

How long does it take for the increased dosage of Fluoxetine to work? 

The full action of an increased dose of Fluoxetine can be felt from 4 to 6 weeks after the dosage goes up. The same is true for when you just started to take the medication. 

It takes this long for the medication to work because the level of it needs to be high in your system for it to have the appropriate effect.And as your dosage goes up, around that time you will start to experience the benefits of the higher dosage. 

The dosage setting will depend on how intense your condition is, the symptoms you have been experimenting with, and your body structure. And once your doctor prescribes you Fluoxetine, you may begin to feel some small changes from one or two weeks after you have started.

The dosage of Fluoxetine may vary between 20mg and 80mg when they are taken once a day. At first, your doctor may start you off with the lowest dosage of 20mg, and follow you through during the first few weeks. With time, and when needed they can make your dosage higher until it reaches the level your doctor has in mind.

You should only take the medication as prescribed by your doctor, and if you ever miss a dose, take it as soon as you can. Unless it is close to your next dosage, then you should wait for the next one.

Along with that, you should never stop taking the medication without discussing it with your doctor since it can lead to many withdrawal symptoms such as dizziness, confusion, trouble sleeping and nightmares, excessive crying, and irritability.

What is Fluoxetine?

Fluoxetine, which is also known as Prozac, is an antidepressant medication. It was created in the 1980s, and it is a form of antidepressant called Selective Serotonin Reuptake Inhibitors (SSRI).

It is usually used to treat Major Depressive Disorder, Obsessive-Compulsive Disorder, Panic Disorder, Bulimia Nervosa, and Premenstrual Dysphoric Disorder.

How does Fluoxetine work? 

Like other SSRI antidepressants, Fluoxetine works by preventing the brain from reabsorbing serotonin. It improves the person’s mood since they might be experiencing low levels of serotonin, and the medication improves that. 

It has been shown that the use of Fluoxetine can make the brain more plastic, which can allow therapy to have greater results in the person’s treatment. 

When you are taking Fluoxetine you may start to feel more relaxed, and the intensity of your depression or anxiety may decrease. Your sleep and eating patterns can improve, along with your ability to focus and your energy level.

How long does it take for the increased dosage of Fluoxetine to work?

What are the side effects of Fluoxetine? 

Although the use of Fluoxetine can help people with many mental health issues, some people may experience some side effects. The most common side effects can be anxiety, diarrhea, dizziness, dry mouth, fatigue, headaches, loss of appetite, nausea, and sleep problems.

Along with that, it can cause changes in libido, sexual activity, and sweating. And even though those are the most common side effects, there are some rare ones such as bleeding, fever, seizures, allergic reactions, suicidal thoughts, swelling, and trouble breathing and swallowing.

People usually go through the most common side effects on the first days or weeks when they take the medication, and as your body gets used to it, it gets better. But if you have the rarest types of side effects, or if they go on for a prolonged period, you might want to discuss with your doctor about adjusting your dosage or changing Fluoxetine for another medication.

What are matters to be careful with?

Fluoxetine hasn’t been connected to addiction. And even though Fluoxetine is a completely safe drug, some matters need to be taken into consideration when you and your doctor are thinking of putting you on the medication.

One thing to consider is that you shouldn’t take it with illegal drugs since it can make your condition worse, or decrease the benefits of the medication. 

Along with that, you should consider if you are thinking about getting pregnant. That is because using antidepressants from week 13 until the end of the pregnancy can bring troubles to the baby, and you can even go into labor before it is fully formed. It can also lead, although it is rare, to lung problems for the baby.

You should also tell your doctor about all the other medications you are taking so they can see if there will be any negative interactions between them. It especially shouldn’t be used with aspirin, due to bleeding, and supplements. It should also be discussed with the doctor when taken by people over 65 years old. 

Frequently Asked Questions (FAQ): How long does it take for the increased dosage of Fluoxetine to work? 

What are the forms of depression?

Depression can happen in mild, moderate, major, and persistent forms. In all of them the person may experience the common symptoms of depression, but what changes from one to the other is how intense they are, and how long they go on.

The mild depression lasts only a few weeks, and its symptoms are so mild that it can make it hard for the condition to be diagnosed. When someone is going through mild depression, they may make some lifestyle changes as a way to cope with it.

In moderate depression, the person may experience the symptoms for a little longer, and they can impact their lives. People with moderate depression usually treat it with therapy, but in some cases, people may benefit from medication.

Major depression is the most intense form of depression. It can make it harder for people to maintain their life as it was before, and even simple things such as getting out of bed can be impossible at times. 

Aside from the regular symptoms of depression, people with major depression can also experience hallucinations, become delusional, or even experience psychotic episodes.

To treat major depression the person will need a combination of medication and therapy. Persistent depression is a form of depression that can go on for about 5 years. 

During this period, the person will swing from mild depression to major depression. To handle those swings, the person must follow through in their treatment with medication, and therapy.

Can I change my medication by myself?

No, you shouldn’t change your medication by yourself, nor should you self-medicate. With antidepressants, this is a hard thing to do since they need to be prescribed by a doctor. 

But if you are already taking one medication, and have found some information on a medication you think will suit you better, you may gather all the information, and make an appointment with your doctor.

In that, you can tell them why you are considering changing your medication, how you have been feeling with the one you are already taking, and what you think will improve with the new one. They will analyze it, and if they consider this new medication appropriate to treat your condition, they may prescribe it for you.

When they do, they will explain to you how you should stop your old medication little by little, so you don’t experience withdrawal symptoms. And not only that, they will explain to you how to start the new medication little by little so you don’t experience a lot of side effects.

Why do people experience different effects with the same medication?

This happens because each organism reacts differently to things. While for someone medication can have very few side effects and can improve their condition. To others that are going through the same dosage and condition, it can be not that helpful, and the side effects can be intense.

That is why it is extremely important to be accompanied by a mental health professional. By giving back to them the feedback on how you feel, they will be able to adjust your treatment as necessary. They may change your dosage or even change the medication if it is necessary.

What are the causes of depression?

Depression is a multi-factor condition, so it is hard to determine what caused a person to become depressed. But what is known is that it can be related to genetics, so when you have a family history of depression, it may be easier for you to develop the condition. In the same way, women seem to have a higher chance of becoming depressed.

It can also happen when you experience a chemical imbalance in your brain. Or when you are going through a traumatic experience, such as the loss of a loved one, the end of a relationship, or even going through financial or legal problems. 

What are antidepressants?

Antidepressants are the type of medication people take when they are going through a depressive episode. The most often prescribed is Selective serotonin reuptake inhibitors (SSRIs). This is because they usually have fewer side effects, Fluoxetine and Citalopram are part of this form of antidepressant.

Another form of antidepressant is the Serotonin-noradrenaline reuptake inhibitors (SNRIs). This was created to be more effective than SSRI. An example of SNRIs is venlafaxine.

As for Noradrenaline and specific serotonergic antidepressants (NASSAs), they are usually recommended to people that can’t take SSRIs. They can have some strong side effects, and an example of it is mirtazapine.

There are older forms of antidepressants such as tricyclic antidepressants (TCAs), they can be recommended to people with major depression that are resistant to other medications. An example of it is amitriptyline. 

Serotonin antagonists and reuptake inhibitors (SARIs) are a form of antidepressants that is also prescribed when other forms haven’t worked. An example of it is trazodone. 

There are Monoamine oxidase inhibitors (MAOIs) that are an older type of antidepressant. It has a lot of serious side effects. The most known example of it is tranylcypromine.


This article showed how long it takes for the higher dosage of Fluoxetine to work in your body. For that, the article explained what Fluoxetine is, how it works in your body, and its most common side effects.

If you have any questions or comments about this article, feel free to write them in the section below.