Best Probiotic Brand for Anxiety (15+ List)

Here is an extensive list of the best probiotic brands for anxiety. This short article will first explain how probiotics can reduce symptoms of anxiety. Then, we will explore these brand options and discuss their unique benefits.

What are the Best Probiotic Brands for Anxiety?

We picked out the best probiotic brands that you can consume daily to fight with anxiety. Here are the top ones:

Top Brands for Probiotics that Help Anxiety

Taking probiotics is a growing trend, especially among teenagers who engage in sports. These are mostly recommended by their coaches to improve their digestion and athletic performance. However, probiotics are good for everyone since they help with immunity and mental wellbeing.

Recent studies have found that there is a gut-brain connection that can be accessed through probiotic supplements. Basically, these “helpful” bacteria replenish the flora inside our intestines and enhance the absorption of nutrients.

As a result, the body increases the activity of the sympathetic nervous system, which is the antithesis of anxiety. There are plenty of supplement brands that are capitalising on this new research to sell probiotics as an anxiety-relief.

Here are the top brands for probiotics that will help you lower your anxiety:

Care/of Probiotic Blend

This is a blend created to give consumers a harmonious gut. It helps you naturally regulate your digestive system. It contains two types of helpful bacteria. The first is Bifidobacterium lactis, of which this blend has 4 billion CFUs. 

In 2019, a double blind, randomized, placebo-controlled trial demonstrated that B. lactis reduced symptoms of generalised anxiety disorder. 

The second good bacteria in Care/of Probiotic Blend is 1 billion CFUs of Lactobacillus acidophilus. It can positively affect both depression and anxiety. This product is manufactured in the USA and uses a patented stability technology. 

Mood Probiotic by InnovixLabs

Mood Probiotic is a pack of 60 capsules that contain two strains of anxiolytic bacteria. One of them is Lactobacillus helveticus, which uses the vagal pathway to help you come out of fight-or-flight. 

The second is Bifidobacterium longum that reduces anxiety and improves cognitive function when ingested. 

It is a stress management support that can ease physical and psychological symptoms. It may also promote positive mood balance. This product is vegan, unflavoured and completely free of GMOs, nuts, and gluten.

Probiotic & Prebiotic Supplement by Earth’s Pearl Probiotics

This is a multi-strain probiotic strain that has Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus reuteri, Bifidobacterium infantis, and Bifidobacterium lactis. In addition to improving gut health, these bacteria also improve mood and psychological health. 

Lactobacillus plantarum attenuates anxiety-related behavior and protects against stress. Bifidobacterium infantis has also demonstrated positive effects on mental health. This is a yeast-free product but it contains milk.

Persona Daily Probiotic

Persona’s Daily Probiotic has triple benefits that improve quality of life. Daily consumption of this product supports healthy digestion, bolsters immunity, and improves emotional wellbeing. 

These are vegetarian capsules containing Lactobacillus rhamnosus, which is a bacteria that helps you fight anxiety. Studies have also shown that this is an effective treatment to reduce symptoms of postpartum depression and anxiety.

Dr. Ohhira’s Probiotics by Essential Formulas

Dr. Ohhira Probiotics are 100% vegetarian, dairy-free, gluten-free, chemical-free, and non-GMO. These are a wide range of products that use probiotics for various health-boosting properties. 

You can try them in the form of drinks, capsules, oils, and beauty or skin-care products. The Reg’ Activ series is a collection of probiotic supplements that contain Lactobacillus fermentum. This is a strain that’s great for anxiety because it has shown psychotropic properties by altering serotonergic pathways during stress.

Dr. Formulated Probiotics Mood+ by Garden of Life

Here is a pack of 60 vegetarian, probiotic capsules comprising 16 different strains that help with digestion, immunity, and mood. These are made with ashwagandha, alaskan blueberries and acacia fiber. 

While the latter two are excellent for physical health, ashwagandha is a known adaptogen for anxiety. The Mood+ capsules combine the goodness of these helpful bacteria and natural extracts to help you fight anxiety better.

Revly by Amazon Women’s Probiotic

Amazon’s brand Revly offers many different dietary supplements that aid women’s health. This is a pack of vegetarian capsules containing two proprietary blends of good bacteria. Its Lactobacillus blend is a mix of Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus lactis, Lactobacillus salivarius, and Lactobacillus plantarum. 

The Bifidobacterium blend has strains of Bifidobacterium lactis and Bifidobacterium breve. Together, these not only help in digestion but also reduce symptoms of anxiety.

Mood Probiotics and Prebiotics Drinkable Powder by Biolever

Mood Probiotics by Biolever is a drink that helps to reduce occasional gastrointestinal symptoms related to stress. It does so by lowering cortisol levels in the body, which is a common stress hormone. 

This is a blend of Lactobacillus helveticus and Bifidobacterium longum. As discussed earlier, both these strains effectively lower anxiety in the mind and body if ingested. This drink contains no sugar, colouring, flavour, or preservatives.

Mood-Boosting Probiotic by Lifted Naturals

These capsules are a probiotic blend of B. infantis, B. longum, B. lactis, L. planatarum, L. acidophilus, B. animalis, L. helveticus, and L. rhamnosus. One new strain of bacteria we haven’t talked about yet is Bifidobacterium animalis. 

This too is a useful bacteria that has been shown to indirectly improve mental health by enhancing gut performance. These pills are dairy-free and gluten-free. They do not require refrigeration.

Syn-rgy Biome Active 

Biome Actives is an innovative formula with inulin and Bacillus coagulans. Inulin is a prebiotic fiber that is a frequent ingredient in most protein bars. It belongs to a class of dietary fibers known as fructans and is good for digestion. 

Bacillus coagulans is a lactic-acid-producing species. It has been associated with the alleviation of symptoms of anxiety and depression. Syn-rgy offers a 90-day money-back guarantee on all its products, so go ahead and try some of this supplement.

Organixx Probiotixx+

Probiotixx+ capsules create a balanced gut barrier and support the flow of nutrients into your bloodstream. These pills are plant-based, vegetarian ones that help with digestion, immunity, and mood. 

The single Lactobacillus plantarum will multiply in your gut and break down carbs and protein for less gas, cramps, and bloating. This product had an unmatched money-back guarantee of 365 days. That’s how confident the makers are that this supplement will improve your life.

PRO-15 Advanced Strength Probiotic and Kiwi Extract by Hyperbiotics

This is an advanced strength probiotic blend with kiwi extracts. It creates a microenvironment inside your digestive system to encourage nutrient absorption. This may even help you feel happy and energetic. 

These daily tablets have 15 different strains of helpful bacteria. Additionally, the kiwi powder supports colon health while helping your probiotics colonise within your intestinal tract. PRO-15 is vegetarian, dairy-free, gluten-free and uses a time-release design.

Optimal Biotics

This is a superior and evidence-based probiotic formulation designed to lift your mood and lower stress and anxiety. Each pack has 60 spheres containing L. acidophilus, B. bifidum, L. casei, L. rhamnosus, L. reuteri, B. breve, B. longum, and S. thermophilus. These capsules are shelf-stable, delayed-release, and dairy-free. 

A systematic review done in 2019 revealed that B. bifidum can be used in the treatment of anxiety, depression, and related symptoms. A similar meta-analysis showed the same for S. thermophilus.

Daily Probiotic Time Release Pearls by Replenish The Good

Daily Probiotic is a 60-day supply for time-release capsules containing L. acidophilus, L. plantarum, B. lactis, L. brevis, L. rhamnosus, and B. longum. 

This product is more effective than probiotic capsules because the carrier structure is a  patented time release BIO-tract system named pearls. These pearls are vegetarian, yeast-free, lactose-free and have no sugar, flavour, or preservatives.

Matchabiotics Probiotic Supplement by Distinctly Organics

MatchaBiotics PRO-15 also uses patented smartcaps instead of regular capsules to protect contents through stomach acids. A daily consumption of this product will improve mood, fight stress, and promote memory and concentration. 

It will also enhance digestion, immunity, and accelerate weight loss. In addition to 10 helpful strains of bacteria, these smartcaps also contain organic matcha powder that is also a known adaptogen.

New Chapter Mood Support Probiotic

Enhance you well-being and reduce occasional anxiety with this powerful mood-boosting probiotic supplement. This is a pack of 30/60 vegan, gluten-free, non-GMO capsules that serve as a mood support. 

The capsules are made of probiotics to replenish good bacteria, targeted herbs to uplift mood, and prebiotics that act as fuel. Herbs used in it are lavender, chamomile, lemon balm, and Jerusalem artichoke. The suggested use is one capsule daily for people above the age of 12. These can be taken even on an empty stomach.


Here was an extensive list of the best probiotic brands for anxiety. This short article first explained how probiotics can reduce symptoms of anxiety. Then, we explored these brand options and discussed their unique benefits.

The probiotic brands mentioned here were Care/of Probiotic Blend, Mood Probiotic by InnovixLabs, Probiotic & Prebiotic Supplement by Earth’s Pearl Probiotics, Persona Daily Probiotic, Dr. Ohhira’s Probiotics by Essential Formulas, Dr. Formulated Probiotics Mood+ by Garden of Life, Revly by Amazon Women’s Probiotic, Mood Probiotics and Prebiotics Drinkable Powder by Biolever, Mood-Boosting Probiotic by Lifted Naturals. 

Some more brands were Syn-rgy Biome Active, Organixx Probiotixx+, PRO-15 Advanced Strength Probiotic and Kiwi Extract by Hyperbiotics, Optimal Biotics, Daily Probiotic Time Release Pearls by Replenish The Good, Matchabiotics Probiotic Supplement by Distinctly Organics, New Chapter Mood Support Probiotic

FAQs (Best Probiotic Brand for Anxiety)

How quickly do probiotics work for anxiety?

Different people report varying timelines for the effects of probiotics on their anxiety. Some people may start seeing the impact within a few days while others may take a couple of weeks. Typically, it takes 4-8 weeks and the variation depends on your body’s sensitivity. But no matter how sensitive you are, it will take at least a few days to start showing any effect.

What is the best probiotic for mood?

There are many probiotic strains that are highly effective in balancing mood. Some of these are L. acidophilus, B. bifidum, L. casei, L. rhamnosus, L. reuteri, B. breve, B. longum, and S. thermophilus.

Can probiotics make anxiety worse?

This depends on how much you consume in a day. Taking more than 20 billion CFUs may cause adverse side effects like gas, bloating, constipation and thirst. Anxiety too is one of the side effects that come with overconsumption.

What are the signs you need probiotics?

Some signs that you could use probiotic supplements are listed below:
Irregularity in bowel movements
Uncontrollable cravings for desserts
Slow metabolism
Antibiotic consumption due to current or previous infection
Skin-related issues


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