Best Happy Pills for Anxiety (15+ List)

In this short article, we are going to describe the best happy pills one can take for anxiety. The items first described here are psychiatric drugs that require prescriptions. The remaining ones are over-the-counter and made from natural or herbal ingredients.

What are the Best Happy Pills for Anxiety?

The best happy pills that one can take for anxiety are:

Prescription Happy Pills for Anxiety

First, we will talk about some of the prescription drugs that are used as happy pills for anxiety. You need to have a prescription from a licensed practitioner to purchase these:


Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) antidepressant. By inhibiting the uptake of serotonin by nerve cells, it helps people with depression, panic, anxiety, or obsessive-compulsive symptoms. 

Commercially known as Prozac, it works by preventing the brain from reabsorbing naturally occurring serotonin. Serotonin is involved in mood regulation. In this way, it helps the brain to maintain enough serotonin so that you have a feeling of well-being. This well-being is a result of improved communication between brain cells. This will lead to a reduction in anxiety-inducing thoughts, worry and dread.


Sertraline is also an antidepressant in a group of drugs called selective serotonin reuptake inhibitors (SSRIs). It affects chemicals in the brain that may be unbalanced in people with depression, panic, anxiety, or obsessive-compulsive symptoms.

Sold under the brand name Zoloft, it treats anxiety by slowing down the reabsorption of serotonin. Zoloft may treat anxiety if psychological treatments, like CBT, aren’t working. It might also be prescribed if a psychiatrist thinks it will improve someone’s quality of life. The right dosage varies by the severity and comorbidity of anxiety.


Citalopram is often used to treat depression and sometimes for generalised anxiety disorder. It belongs to a group of antidepressants called SSRIs. It helps people recover from depression, and has fewer unwanted side effects than older antidepressants.

Known by the masses as Celexa, it works by increasing the amount of serotonin in your brain. Serotonin is a natural chemical found in your body that helps to regulate mood. It does this by blocking the reuptake of serotonin into nerve cells, which makes more serotonin available in your brain.


A similar antidepressant belonging to the group of SSRIs is Paroxetine. Paroxetine affects the chemicals in the brain that may be disturbed in people with neurotic disorders. Sold under the names of Paxil and Seroxat among others, it is used to treat Major Depressive Disorder. 

Generalized Anxiety Disorder and Major Depressive Disorder are the most common types of anxiety-mood comorbidity. Up to 80% of subjects with lifetime GAD also have a comorbid mood disorder during their lifetime. Paroxetine works by helping to restore the balance of serotonin in the brain.


Another antidepressant belonging to the class of SSRIs is Fluvoxamine. It is used primarily for the treatment of depressive disorder and obsessive-compulsive disorder (OCD).

Sold under the brand name Luvox CR, it works by slowly reabsorbing the chemical serotonin in the brain. Serotonin, as stated above, is believed to play a role in the regulation of mood and anxiety. It was approved by the Food and Drug Administration for the treatment of social anxiety disorder in February 2008.


The last drug belonging to the class of SSRI is Escitalopram. Escitalopram is used to treat depression and anxiety by helping to restore the balance of serotonin in the brain. It may improve your energy level and feelings of well-being and decrease nervousness.

Escitalopram is promoted under the names of Cipralex and Lexapro, among others. Anxiety disorders can develop without any apparent reason, or they might be triggered by an incident. When the symptoms of anxiety occur, taking Escitalopram can help to ease them and restore normal daily routines.

OTC & Natural Happy Pills for Anxiety

Now that we’ve covered the prescription drugs, let’s talk about some natural alternatives. These are non-addictive and don’t cause side effects. Try the following pills made from plant extracts to fight anxiety:

LES Labs Mood Boost

Mood Boost’s natural formula helps relieve occasional stress and anxiety quickly. Its active ingredients are 5-HTP, L-Tyrosine, GABA and L-Theanine. 5-HTP naturally promotes a positive mood. L-Tyrosine and L-Theanine help to relieve stress and anxiety. GABA acts quickly to calm the mind and assists in mood support. 

Mood Boost is also packed with passionflower, ashwagandha, Rhodiola Rosea, and chamomile extracts. These help to promote relaxation and the body’s natural ability to cope with stress.

Tranquil Natural Happy Pills

Tranquil Supplement’s formula was expertly curated to contain the optimal natural mix of adaptogens, herbs and vitamins. Specifically, those that are known to support stress relief, so that you can keep calm and live stress-free. 

It includes 28 healing herbs that have been used for centuries and are considered to be mood enhancers. They provide natural anxiety relief and act as a natural antidepressant. These herbs are Ashwagandha, Rhodiola, St. John’s Wort, Chamomile, Passion Flower, and Valerian. The dosage of each included herb has been scientifically proven to be effective.

Libby In The Mood Daily Wellness Supplement

In The Mood has been created as a clean-label women’s supplement developed to support sleep, mood, and energy in the face of stress. Deal with less-than-perfect diets, environmental pollution, and the side effects of some daily medications, along with this.

This supplement contains Vitamin C, and Vitamin B12, which are known to reduce the cortisol levels in the body, that cause stress. It supports deeper sleep and prevents confusion so that you are prepared to handle everyday pressures.

Go with The Flow

Go With The Flow is a supplement designed to balance hormones and provide relief from perimenopause and menopause symptoms. Absolutely vegan and herbal, it relieves menstrual cramps organically. Created from 100% plant-based ingredients, it consists of 4 powerful herbs. 

They are Chasteberry, Gelatinized Maca Root, Black Cohosh Root, and Dong Quai. The dosage of each herb included has been scientifically proven to provide effective menopause and PMS support. Go With The Flow provides relief from restlessness, mood swings, irritability, nervousness, and lack of energy, resulting due to menstruation.

Be Grounded Stress Relief

Infused with pressure-deflating herbs, Be Grounded stress pills’ lemon balm formula quickly nourishes your “situation-deflectors”. Situation deflectors are feelings of anxiety, guilt, shame, etc. that help people feel less pain and make it through a difficult situation. These pills transform those panicky feelings into blissed-out, zen-filled peace. 

Renowned for their calming, agitation-soothing properties, these lavender-infused calming pills allow you to simmer down aggression, anger and unhappiness. Moreover, they work faster than traditional anti-anxiety pills.

Natural Balance Happy Camper

This next product is created using passionflower, Kava Kava, Eleuthero, Gotu Kola, Kola Nut, Schisandra, wood betony and English lavender. All of these ingredients are known for their anxiety-reducing properties. Several clinical studies show that passionflower has anxiety-calming (anxiolytic) effects. 

Kava extract has a calming, euphoric effect that some people compare with that of alcohol. Eleuthero, schizandra, and Gotu kola help the body fight signs of stress so you feel more balanced and in control. This feel-good herbal formula is all-natural and vegan and is widely used for mood support.

Groovy Nutrition Calm Support

Groovy Nutrition gathered 13 powerful adaptogens like Ashwagandha, St. John’s Wort and GABA to enhance mood and support cognitive function. Furthermore, they did so in the safest natural way, promoting an overall calming effect by increasing serotonin levels. 

Customers have shown an increase in their focus and natural energy in just 2 weeks. While their anxiety and stress lowered after about 3 weeks. These supplements can improve your overall well-being in a month!

A Little Pick Me Up

A Little Pick Me Up Energy Supplement contains the finest American and Asian ginseng. Ginseng is an adaptogen proven to be ideal for supporting boosted adrenal gland performance. 

This way, it aids your body to de-stress and transform that “fight or flight” response into more pure, happy energy. The Nootropic present in this stimulates your mind for sharp, long-lasting focus: Laden with the RICH, Rhodiola Rosea Root and Bacopa extract, it promotes enhanced brain power while calming your mind from distractions.

Dr. Emil Nutrition 5-HTP

This product has supplemented 200mg of pure 5-HTP with clinically proven serotonin synthesizers, SAMe and L Tryptophan. Tryptophan is metabolized into 5-HTP in the body, while SAMe is a well-known serotonin booster. 

5-HTP is the primary precursor to serotonin production in the body. Increased levels of serotonin have been scientifically shown to promote positive mood, anxiety relief and better sleep. All Dr Emil products are made from all-natural vitamins, minerals and herbal extracts, without the use of harmful additives.

Love Wellness #Mood Pills

Love Wellness’ supplements are perfect for all women, looking to reduce stress, improve mood or deal with pesky hormones. Its active ingredients are GABA, Ginkgo Biloba and L-Theanine. GABA is a naturally occurring amino acid to help with stress and fatigue. Ginkgo Biloba helps with mood & cognitive function and L-Theanine helps to reduce anxiety.

Additionally, this product is vegan, gluten-free and dairy-free. Mood Pills are specifically formulated with a woman’s body and personal care in mind. So she feels confident and healthy every day.


Joy-filled supplements contain 7 healing herbs that have been used for centuries and are considered to be mood enhancers. They provide natural anxiety relief and act as a natural antidepressant. The herbs help to increase the production of GABA, which works to reduce restlessness. 

Other herbs such as Rhodiola Rosea and Ginkgo Biloba support a healthy response to stress by decreasing cortisol levels. The dosage of each herb included in this has been scientifically proven to be effective. The collection of herbs works harmoniously together to act as an antidepressant.


In this short article, we described the best happy pills one can take for anxiety. The items first described here were psychiatric drugs that require prescriptions. The remaining ones were over-the-counter and made from natural or herbal ingredients.

Happy pills that help with anxiety include Fluoxetine, Sertraline, Citalopram, Paroxetine, Fluvoxamine, Escitalopram, LES Labs Mood Boost, Tranquil Natural Happy Pills, Libby In The Mood Daily Wellness Supplement, Go with The Flow, Be Grounded Stress Relief, Natural Balance Happy Camper, Groovy Nutrition Calm Support, A Little Pick Me Up, Dr. Emil Nutrition 5-HTP, Love Wellness #Mood Pills, and Joy-Filled.

FAQs (Best Happy Pills for Anxiety)

What drug is a happy pill?

The term ‘happy pill’ refers to prescription drugs that psychiatrists use for treating conditions like anxiety and depression. Some common names associated with this term are Prozac and Valium. These are generally taken to improve mood and lower anxious stress.

What is the best medication for anxiety and mood swings?

There are many different medicines used for anxiety and mood swings and their effects vary from person to person. However, most common drugs for these conditions include SSRIs and SNRIs. Some doctors also prescribe benzodiazepines like Xanax and Valium.

What is the most calming antidepressant?

The effects of medication like antidepressants can vary from person to person. Some of the usual antidepressants prescribed by psychiatrists are Prozac, Zoloft, Celexa, and Lexapro.


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