Best 5-HTP for Anxiety (15+ List)

This is an extensive list of the best 5-HTP supplements available online. Some of these are in powder form while others are capsules. Add any of these to your daily nutrition to improve your resistance to anxiety.

What is the Best 5-HTP for Anxiety?

We have listed below the top 5-HTP supplements for anxiety:

5-HTP Supplements to Fight Anxiety

5-HTP is one of the trending dietary supplements Dietary supplements containing 5-HTP may elevate serotonin levels, causing an improvement in mood. However, studies using PET scans have found that overactivity of serotonin is associated with anxiety disorders. One must be careful when consuming these supplements. Always consult a doctor or nutritionist to know what dose is right for you. 

Farnoush Khodarahmi, a naturopathic medic, recommends the usage of 5-HTP, but with caution, for disorders like anxiety and depression. These supplements are claimed to help promote feelings of happiness and general well-being. They also have a wide range of other positives such as appetite control, reduced anxiety, and improved mood, sleep and feelings of relaxation.

Swanson 5-HTP Maximum Strength

Some natural medicine proponents believe that taking 5-HTP supplements can help reduce anxiety and panic. One research study found that taking 5-HTP reduced anxiety and panic in people with psychological disorder. 

Swanson supports production of serotonin, which regulates mood, and is a precursor to melatonin. Along with these capsules, you will be able to take care of your mental and emotional wellbeing. It will help you have a healthier and balanced mood.

Dr. Emil Nutrition 5-HTP

This second item on the list has supplemented pure 5-HTP with clinically proven serotonin synthesizers, SAMe and L Tryptophan. This led it to be a super booster! 5-HTP alone has been known to reduce anxiety symptoms in people with anxiety disorders.

Tryptophan is metabolized into 5-HTP in the body, while SAMe is a well-known serotonin booster. Both of these ingredients have also been known to help 5-HTP conversion to serotonin, creating the ideal synergistic mood booster.

Arazo Nutrition

Arazo Nutrition contains 5 HTP and calcium. Its high purity of 99% makes it super potent, unlike other brands with low purity of 80% or less. These capsules boost benefits for immediate positive mood, sleep and anxiety support. All of these 3 symptoms are interrelated. 

Anxiety can lead to sleeplessness and vice-versa. People with anxiety are troubled with constant negative thoughts which makes them emotionally dysfunctional. 5-HTP has been used for sleep disorders such as insomnia, depression, anxiety, and other debilitating mental illnesses.

Natrol 5-HTP

Natrol mood enhancers promote a positive mood, helps control your appetite and supports normal sleep. Regular use of 5-HTP helps to naturally balance your body’s own levels of serotonin. Serotonin is a chemical messenger that affects emotions, behaviour, appetite, thoughts and sleep. 

Today’s stress-filled lifestyles and dietary practices may negatively alter serotonin levels, which can cause irritability and emotional blues. So do not ignore your mental health needs. Take charge of it right now, with Natrol 5-HTP!

Nested Naturals 5-HTP

Both animal studies and human clinical trials show that 5-HTP has anti-anxiety effects. There is some evidence that 5-HTP may also inhibit panic attacks induced by carbon dioxide. It is famously known to be a precursor to serotonin. 

Serotonin is a neurotransmitter that has been linked to positive moods, anxiety relief and good sleep.This naturally-sourced nutrient can do wonders by keeping your level of serotonin stable and high. By doing this, it also improves your sleep! Nested Naturals is 100% vegan, non-GMO, gluten-free, soy-free and allergen-free. 


On top of having 5-HTP as an active ingredient, this supplement also includes magnesium and Valerian Root. These help to promote a good mood and a state of relaxation. Because of the overactivity of the Sympathetic Nervous System during an anxiety attack, the body fails to rest.

 The constant fight-or-flight response, makes you feel fatigued and worn-out even when you are physically not doing anything. This product’s amazing concoction has all the necessary nutrients to reduce these symptoms and make you feel happier and healthier.

NOW Supplements

5-HTP is the intermediate metabolite between the amino acid L-tryptophan and serotonin. It supports the production of serotonin in the brain and Central Nervous System. Serotonin can impact sleep, mood, appetite, and body temperature. 

These things are mostly affected when you are prone to anxiety attacks or have GAD. By controlling the physiological responses of the body for anxiety, it also reduces the psychological effects. You will be able to have a better slumber, a happier mood and a normal appetite.

Nutricost 5-HTP

In the field of integrative psychiatry, prescription medications and natural supplements are often used in combination to improve treatment response. This reduces side effects that may be caused when medications are taken alone. 

5-HTP is a natural supplement that may be safely combined with prescribed anti-anxiety medication with little risk of adverse effects. Nutricost 5-HTP supplements can be the perfect one, if you have symptoms of anxiety and panic disorder. Take them along with your daily diet to feel calm and content!

Myprotein 5-HTP capsules

It is important to get the hours of sleep you need. Whether you’re a committed athlete or not, it’s crucial to get the right amount of rest to restore your body. Low serotonin in the body can lead to a lack of sleep. This in turn, may lead to a myriad of mental health problems like stress, anxiety and depression. 

5-HTP is a compound that the body makes from the amino acid, tryptophan. A precursor to the neurotransmitter serotonin, it is involved in maintaining healthy sleep, cognitive functions and memory.

Jarrow Formulas 5-HTP

Jarrow Formulas 5-HTP, contains 5-HTP, which is a precursor to both serotonin and melatonin. Serotonin is specifically known to improve your mood, which is why it is known as the “happy hormone”. 

Melatonin ensures that we get a healthy amount of sleep. Both of these factors are essential to have good mental health and prevent anxiety. Another distinguishing feature of this product is that it is sourced botanically from Griffonia simplicifolia.

Nature’s Nutrition

5-HTP, when taken gradually, can improve the quality of sleep in chronically anxious patients. Especially those who complain of insomnia. It also reduces the severity of daytime anxiety. Taking 5-HTP as a supplement can help support serotonin in your brain. 

Serotonin can support a positive mood, support occasional sleeplessness, and help you with feelings of stress. Nature’s Nutrition produces their supplements using the highest quality Griffonia simplicifolia available while following current good manufacturing practices.


Toniiq’ ultra-high purity and strength sets it apart from its competitors. These capsules contain 200mg of the highest purity 5-HTP powder in each pill. They are ethically sourced from family owned farms in Ghana, grown and cultivated using an extraction process to ensure 99% standardized purity. 

Serotonin levels can be boosted by supplementing with 5-HTP. The more of this natural chemical present, the happier you are, hence its reputation as the happy hormone.

Pure Encapsulations 5-HTP

5-HTP supplements are thought to treat anxiety by increasing serotonin levels. 5-HTP is said to help with migraines, which are throbbing headaches that are often accompanied by nausea, stress or anxiety. 5-HTP produces serotonin, which can be converted into the hormone melatonin. 

Melatonin plays an important role in regulating sleep. Its levels begin to rise in the evening to promote sleep and fall in the morning to wake you up. These supplements are made with only premium ingredients sourced from trusted suppliers and guided by our nutritional experts.

Doctor’s Best 5-HTP Enhanced

Doctor’s Best 5-HTP contains a naturally occurring metabolite of the amino acid tryptophan. 5-HTP is extracted from the seeds of the Griffonia simplicifolia plant. Vitamin B6 and C are important cofactors in the 5-HTP’s conversion to serotonin. 

Serotonin regulates anxiety, happiness, and mood. Low levels of the chemical have been associated with anxiety, and increased serotonin levels brought are thought to decrease arousal.


5-HTP is a natural precursor to serotonin It is the “feel good” brain chemical that helps regulate our moods and promotes the reduction of anxiety and stress. Human bodies produce 5-HTP naturally. However, due to malfunctioning of the nervous system, its production might get affected. 

Taking a supplement which is naturally derived from the Griffonia plant, can aid in betterment of the mind. This supplement also includes vitamin B6 to catalyze the conversion of 5-HTP to serotonin. Serotonin leads to better temper, complete sleep and great mental health.

Horbaach 5-HTP

5-HTP is a drug-free naturally occurring substance that helps support healthy mood balance and relaxation. 5-HTP and Tryptophan are known precursors to Serotonin, that the body utilizes to regulate behavioural disposition and sleep patterns. 

It’s hard to get the benefits of HTP-5 from any foods. However, there are a variety of pure, nutritional supplements that contain 5-HTP extract for better health. This supplement is one of them! Its ingredients support a positive mood, mental focus, normal sleep patterns, and healthy craving control.

Side Note: I have tried and tested various products and services to help with my anxiety and depression. See my top recommendations here, as well as a full list of all products and services our team has tested for various mental health conditions and general wellness.


This was an extensive list of the best 5-HTP supplements available online. Some of these are in powder form while others are capsules. Add any of these to your daily nutrition to improve your resistance to anxiety.

Our list included Swanson 5-HTP Maximum Strength, Dr. Emil Nutrition 5-HTP, Arazo Nutrition, Natrol 5-HTP, Nested Naturals 5-HTP, Solgar, NOW Supplements, Nutricost 5-HTP, Myprotein 5-HTP capsules, Jarrow Formulas 5-HTP, Nature’s Nutrition, Toniiq, Pure Encapsulations 5-HTP, Doctor’s Best 5-HTP Enhanced, NatureWise, and Horbaach 5-HTP.

FAQs (Best 5-HTP for Anxiety)

How long does 5-HTP take to work for anxiety?

It will take two to three weeks for effects to start showing and you will have to gradually increase your dose. Start by taking 50 mg and slowly build up to 200 to 300 mg every night before bed. This improves the quality of sleep and reduces the severity of daytime anxiety.

Is it better to take 5-htp at night or in the morning?

Consuming 5-HTP has a tendency to make one feel drowsy. That’s why it is better to take these at night or just before whenever you go to bed.

Can you suddenly stop taking 5-HTP?

Suddenly stopping your 5-HTP supplementation may not be a good idea. Some people report feeling dizzy, tired, or in a low mood if they stop taking it without weaning it out. It’s best to slowly reduce the dosage till you eventually stop entirely.



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